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Diggle, 2016: Overview of all reported CHOR-PDE10A patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
B
PAK
5
5
Yes
Chorea
Hyperreflexia
Dysarthria
Dyskinesia
Tremor (any or unspecified)
Cerebellar signs
Gait impairment
Motor delay
Tremor, intention
Cognitive impairment
-Motor symptoms
Show more (+8)
n.a.
No
B
PAK
n.a.
15
Yes
Chorea
Dysarthria
Hyperreflexia
Gait impairment
-Motor symptoms
Dyskinesia
Show more (+3)
n.a.
No
B
PAK
3
3
Yes
Chorea
Dysarthria
Hyperreflexia
Dyskinesia
Motor delay
-Motor symptoms
Show more (+3)
n.a.
No
B
PAK
n.a.
16
Yes
Gait impairment
-Motor symptoms
Myoclonus
Dyskinesia
Dystonia, oromandibular
Chorea
Dysarthria
Motor delay
Show more (+5)
Gait impairment
Yes
C
FIN
0
n.a.
Yes
Dysarthria
Gait impairment
Delayed speech and language development
Motor delay
-Motor symptoms
Chorea
Dyskinesia
Show more (+4)
n.a.
No
C
FIN
0
n.a.
Yes
Dyskinesia
Dysarthria
-Motor symptoms
Gait impairment
Seizures
Motor delay
Delayed speech and language development
Chorea
Show more (+5)
n.a.