Bruni, 2004: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
n.a.
|
ITA
|
22
|
51
|
n.a.
|
Motor fluctuations
Autonomic dysfunction Cerebral atrophy Dysarthria Dystonia (any or unspecified) Mental deterioration Cerebellar atrophy Ataxia Psychosis Behavioural abnormality Rigidity Show more (+8) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
63
|
n.a.
|
Behavioural abnormality
Rigidity Anxiety Cerebral atrophy Autonomic dysfunction Apathy Psychosis Dysarthria Dystonia (any or unspecified) Cerebellar atrophy Ataxia Mental deterioration Show more (+9) |
Behavioural abnormality
|
|
No
|
♂
|
n.a.
|
ITA
|
20
|
60
|
n.a.
|
Dysarthria
Apathy Psychosis Mental deterioration Behavioural abnormality Dystonia (any or unspecified) Seizures Autonomic dysfunction Ataxia Rigidity Show more (+7) |
n.a.
|
|
No
|
♀
|
n.a.
|
ITA
|
35
|
44
|
n.a.
|
Mental deterioration
Cerebellar atrophy Behavioural abnormality Psychosis Depression Apathy Anxiety Ataxia Dysarthria Rigidity Cerebral atrophy Dystonia (any or unspecified) Show more (+9) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
42
|
n.a.
|
Behavioural abnormality
Cerebral atrophy Dystonia (any or unspecified) Mental deterioration Ataxia Autonomic dysfunction Dysarthria Cerebellar atrophy Rigidity Show more (+6) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
53
|
65
|
n.a.
|
Behavioural abnormality
Autonomic dysfunction Mental deterioration Dysarthria Ataxia Rigidity Show more (+3) |
Behavioural abnormality
|
|
Yes
|
♀
|
n.a.
|
ITA
|
26
|
40
|
n.a.
|
Apathy
Cerebellar atrophy Walking aids Mental deterioration Muscle weakness Wheelchair Tremor (any or unspecified) Myoclonus Behavioural abnormality Cerebral atrophy Muscle atrophy Rigidity Gait ataxia Ataxia Seizures Slow saccades Dystonia (any or unspecified) Dysarthria Dysphagia Dystonia, limb Mutism Depression Autonomic dysfunction Show more (+20) |
Apathy
Behavioural abnormality Gait ataxia |