Bruni, 2004: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
n.a.
|
ITA
|
22
|
51
|
n.a.
|
Cerebral atrophy
Dysarthria Cerebellar atrophy Motor fluctuations Rigidity Ataxia Autonomic dysfunction Mental deterioration Behavioural abnormality Dystonia (any or unspecified) Psychosis Show more (+8) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
63
|
n.a.
|
Psychosis
Autonomic dysfunction Anxiety Mental deterioration Ataxia Cerebellar atrophy Behavioural abnormality Dysarthria Apathy Rigidity Dystonia (any or unspecified) Cerebral atrophy Show more (+9) |
Behavioural abnormality
|
|
No
|
♂
|
n.a.
|
ITA
|
20
|
60
|
n.a.
|
Apathy
Behavioural abnormality Autonomic dysfunction Seizures Dysarthria Mental deterioration Psychosis Dystonia (any or unspecified) Rigidity Ataxia Show more (+7) |
n.a.
|
|
No
|
♀
|
n.a.
|
ITA
|
35
|
44
|
n.a.
|
Dysarthria
Apathy Mental deterioration Psychosis Ataxia Dystonia (any or unspecified) Behavioural abnormality Depression Anxiety Rigidity Cerebral atrophy Cerebellar atrophy Show more (+9) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
33
|
42
|
n.a.
|
Dystonia (any or unspecified)
Rigidity Mental deterioration Cerebral atrophy Ataxia Dysarthria Behavioural abnormality Autonomic dysfunction Cerebellar atrophy Show more (+6) |
Behavioural abnormality
|
|
No
|
♀
|
n.a.
|
ITA
|
53
|
65
|
n.a.
|
Rigidity
Mental deterioration Ataxia Behavioural abnormality Autonomic dysfunction Dysarthria Show more (+3) |
Behavioural abnormality
|
|
Yes
|
♀
|
n.a.
|
ITA
|
26
|
40
|
n.a.
|
Autonomic dysfunction
Apathy Muscle weakness Tremor (any or unspecified) Dysphagia Ataxia Mental deterioration Walking aids Mutism Myoclonus Cerebral atrophy Depression Cerebellar atrophy Dysarthria Seizures Rigidity Gait ataxia Behavioural abnormality Slow saccades Muscle atrophy Dystonia, limb Dystonia (any or unspecified) Wheelchair Show more (+20) |
Apathy
Gait ataxia Behavioural abnormality |