Rolfs, 2003: Overview of all reported ATX-TBP patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
n.a.
|
DEU
|
n.a.
|
60
|
n.a.
|
Depression
|
||
No
|
♂
|
n.a.
|
DEU
|
18
|
20
|
n.a.
|
Slow saccades
Dysarthria |
Dysarthria
|
|
No
|
♀
|
n.a.
|
DEU
|
18
|
38
|
n.a.
|
Ataxia, limb
Mental deterioration Hypogonadotropic hypogonadism Ataxia Nystagmus Mutism Dysphagia Dysarthria Tremor, kinetic Gait ataxia Tremor (any or unspecified) Cerebellar atrophy Show more (+9) |
Mental deterioration
Gait ataxia |
|
No
|
♂
|
n.a.
|
DEU
|
18
|
44
|
n.a.
|
Ataxia, limb
Dysarthria Cerebellar atrophy Mental deterioration Gait ataxia Dysphagia Apraxia Ataxia Cerebral atrophy Show more (+6) |
Mental deterioration
Ataxia |
|
No
|
♀
|
n.a.
|
DEU
|
n.a.
|
42
|
n.a.
|
Slow saccades
Ataxia, limb Apraxia Gait ataxia Autonomic dysfunction Dystonia (any or unspecified) Cerebral atrophy Chorea Dysphagia Dysarthria Cerebellar atrophy Ataxia Mental deterioration Behavioural abnormality Psychosis Show more (+12) |
Psychosis
|
|
No
|
♂
|
n.a.
|
DEU
|
43
|
45
|
n.a.
|
Gait ataxia
|
||
No
|
♀
|
n.a.
|
DEU
|
n.a.
|
47
|
n.a.
|
Chorea
Dysarthria Mental deterioration Slow saccades Depression Dysphagia Ataxia, limb Cerebellar atrophy Psychosis Cerebral atrophy Dystonia (any or unspecified) Ataxia Apraxia Postural tremor, upper limb Behavioural abnormality Atrophy/degeneration affecting the brainstem Gait ataxia Show more (+14) |
Depression
Psychosis |
|
No
|
♂
|
n.a.
|
DEU
|
23
|
26
|
n.a.
|
Dysarthria
Gait ataxia |
||
Yes
|
♂
|
n.a.
|
DEU
|
18
|
51
|
n.a.
|
Ataxia, limb
Ataxia Dystonia (any or unspecified) Cerebellar atrophy Olivopontocerebellar atrophy Show more (+2) |
Ataxia
|
|
Yes
|
♀
|
n.a.
|
DEU
|
30
|
68
|
n.a.
|
Muscle weakness
Cerebellar atrophy Bradykinesia Spasticity Atrophy/degeneration affecting the brainstem Gait ataxia Postural tremor, upper limb Ataxia Parkinsonism Behavioural abnormality Depression Dysarthria Cerebral atrophy Show more (+10) |
Depression
Dysarthria |