Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Bradykinesia
Oculogyric spasms Diurnal fluctuations Psychotic sign/sympt. Dysarthria/anarthria Hypomimia Dyskinesia Gait difficulties/falls Atypical parkinsonism Rigidity NMS parkinsonism Postural instability Parkinsonism Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Bradykinesia
Dystonia Dyskinesia Spasticity/pyramidal signs Atypical parkinsonism Parkinsonism Postural instability Cognitive decline Psychotic sign/sympt. Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Bradykinesia
Psychotic sign/sympt. Postural instability Parkinsonism Cataracts Dyskinesia Respiratory sighs Gaze palsy Rigidity Spasticity/pyramidal signs Atypical parkinsonism Cognitive decline Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Parkinsonism
Respiratory sighs Gaze palsy Psychotic sign/sympt. Autonomic sign/sympt. Bradykinesia Dyskinesia Rigidity Postural instability Cataracts Dysarthria/anarthria Apraxia Atypical parkinsonism Spasticity/pyramidal signs Cognitive decline Show more (+12) |
Bradykinesia
Rigidity |