Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Postural instability
Parkinsonism Dysarthria/anarthria Psychotic sign/sympt. Hypomimia NMS parkinsonism Gait difficulties/falls Bradykinesia Oculogyric spasms Rigidity Atypical parkinsonism Dyskinesia Diurnal fluctuations Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Atypical parkinsonism
Dystonia Cognitive decline Spasticity/pyramidal signs Parkinsonism Bradykinesia Psychotic sign/sympt. Dyskinesia Postural instability Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Parkinsonism
Postural instability Gaze palsy Bradykinesia Rigidity Dyskinesia Atypical parkinsonism Psychotic sign/sympt. Cognitive decline Respiratory sighs Cataracts Spasticity/pyramidal signs Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Cognitive decline
Atypical parkinsonism Respiratory sighs Dyskinesia Gaze palsy Rigidity Cataracts Postural instability Autonomic sign/sympt. Dysarthria/anarthria Psychotic sign/sympt. Bradykinesia Apraxia Parkinsonism Spasticity/pyramidal signs Show more (+12) |
Rigidity
Bradykinesia |