Paisán-Ruiz, 2010: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
TUR
|
17
|
n.a.
|
No
|
Psychotic sign/sympt.
Diurnal fluctuations Dysarthria/anarthria Rigidity Dyskinesia Postural instability Gait difficulties/falls NMS parkinsonism Parkinsonism Bradykinesia Oculogyric spasms Atypical parkinsonism Hypomimia Show more (+10) |
Gait difficulties/falls
|
|
No
|
♀
|
n.a.
|
PAK
|
22
|
22
|
n.a.
|
Cognitive decline
Dystonia Dyskinesia Psychotic sign/sympt. Spasticity/pyramidal signs Parkinsonism Atypical parkinsonism Postural instability Bradykinesia Show more (+6) |
Bradykinesia
|
|
No
|
♀
|
n.a.
|
PAK
|
24
|
44
|
n.a.
|
Respiratory sighs
Dyskinesia Psychotic sign/sympt. Rigidity Bradykinesia Cataracts Gaze palsy Parkinsonism Postural instability Atypical parkinsonism Cognitive decline Spasticity/pyramidal signs Show more (+9) |
Bradykinesia
|
|
Yes
|
♀
|
n.a.
|
PAK
|
17
|
22
|
n.a.
|
Gaze palsy
Apraxia Postural instability Parkinsonism Psychotic sign/sympt. Atypical parkinsonism Cognitive decline Respiratory sighs Rigidity Dyskinesia Spasticity/pyramidal signs Autonomic sign/sympt. Dysarthria/anarthria Cataracts Bradykinesia Show more (+12) |
Rigidity
Bradykinesia |