Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Incontinence
Tremor at rest Rigidity Parkinsonism Bradykinesia Dyskinesia Behavioral abnormalities Dystonia Dysarthria/anarthria Saccadic abnormalities Motor fluctuations NMS parkinsonism Tremor, action Dysphagia Atypical parkinsonism Tremor (any or unspecified) Spasticity/pyramidal signs Postural instability Gaze palsy Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Bradykinesia
NMS parkinsonism Incontinence Dysarthria/anarthria Micrographia Tremor (any or unspecified) Parkinsonism Postural instability Dyskinesia Motor fluctuations Behavioral abnormalities Atypical parkinsonism Spasticity/pyramidal signs Tremor, action Dystonia Tremor at rest Dysphagia Rigidity Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Postural instability
Tremor at rest Spasticity/pyramidal signs Dysphagia Rigidity Dyskinesia NMS parkinsonism Motor fluctuations Tremor (any or unspecified) Bradykinesia Tremor, action Behavioral abnormalities Atypical parkinsonism Parkinsonism Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Motor fluctuations
Spasticity/pyramidal signs Tremor, action Postural instability Rigidity Dyskinesia Tremor (any or unspecified) Behavioral abnormalities Atypical parkinsonism Gaze palsy Saccadic abnormalities Bradykinesia Parkinsonism Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |