Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Rigidity
Postural instability Spasticity/pyramidal signs Tremor, action Tremor at rest Dysphagia Tremor (any or unspecified) Atypical parkinsonism Incontinence Gaze palsy Saccadic abnormalities Behavioral abnormalities Dyskinesia Dysarthria/anarthria NMS parkinsonism Motor fluctuations Parkinsonism Bradykinesia Dystonia Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Rigidity
Motor fluctuations Parkinsonism Postural instability Bradykinesia Micrographia Tremor, action Behavioral abnormalities Atypical parkinsonism NMS parkinsonism Dysarthria/anarthria Dysphagia Incontinence Tremor (any or unspecified) Tremor at rest Spasticity/pyramidal signs Dyskinesia Dystonia Show more (+15) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Dyskinesia
Dysphagia Rigidity NMS parkinsonism Postural instability Bradykinesia Behavioral abnormalities Tremor (any or unspecified) Tremor at rest Atypical parkinsonism Motor fluctuations Parkinsonism Spasticity/pyramidal signs Tremor, action Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Tremor, action
Atypical parkinsonism Tremor (any or unspecified) Behavioral abnormalities Saccadic abnormalities Gaze palsy Postural instability Bradykinesia Dyskinesia Spasticity/pyramidal signs Rigidity Parkinsonism Motor fluctuations Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |