Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Postural instability
Behavioral abnormalities Parkinsonism Saccadic abnormalities Dyskinesia Gaze palsy NMS parkinsonism Motor fluctuations Incontinence Rigidity Dysarthria/anarthria Dysphagia Atypical parkinsonism Spasticity/pyramidal signs Bradykinesia Tremor at rest Dystonia Tremor, action Tremor (any or unspecified) Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Spasticity/pyramidal signs
Incontinence Atypical parkinsonism Dysphagia Parkinsonism Tremor (any or unspecified) Bradykinesia Dysarthria/anarthria Tremor, action Rigidity Behavioral abnormalities Postural instability Dystonia NMS parkinsonism Tremor at rest Dyskinesia Micrographia Motor fluctuations Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Behavioral abnormalities
Atypical parkinsonism Parkinsonism Tremor, action Dyskinesia Bradykinesia Motor fluctuations Dysphagia Postural instability Tremor at rest Spasticity/pyramidal signs NMS parkinsonism Tremor (any or unspecified) Rigidity Show more (+11) |
Behavioral abnormalities
Bradykinesia |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Dyskinesia
Atypical parkinsonism Motor fluctuations Spasticity/pyramidal signs Rigidity Bradykinesia Saccadic abnormalities Gaze palsy Tremor (any or unspecified) Parkinsonism Behavioral abnormalities Postural instability Tremor, action Show more (+10) |
Tremor (any or unspecified)
Behavioral abnormalities |