Di Fonzo, 2009: Overview of all reported PARK-FBXO7 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
ITA
|
13
|
n.a.
|
n.a.
|
Saccadic abnormalities
Dyskinesia Dysarthria/anarthria Parkinsonism Bradykinesia Atypical parkinsonism Tremor, action Incontinence Postural instability Spasticity/pyramidal signs Gaze palsy Dystonia Behavioral abnormalities Motor fluctuations Tremor at rest Rigidity Dysphagia Tremor (any or unspecified) NMS parkinsonism Show more (+16) |
Rigidity
Tremor (any or unspecified) |
|
Yes
|
♀
|
C
|
ITA
|
10
|
n.a.
|
n.a.
|
Dystonia
Motor fluctuations Spasticity/pyramidal signs Atypical parkinsonism Tremor (any or unspecified) Bradykinesia Dysphagia Tremor, action Parkinsonism Dysarthria/anarthria Dyskinesia NMS parkinsonism Incontinence Behavioral abnormalities Postural instability Tremor at rest Micrographia Rigidity Show more (+15) |
Tremor (any or unspecified)
Rigidity |
|
Yes
|
♂
|
C
|
NLD
|
19
|
n.a.
|
n.a.
|
Dysphagia
Tremor (any or unspecified) Postural instability NMS parkinsonism Tremor, action Spasticity/pyramidal signs Tremor at rest Motor fluctuations Bradykinesia Atypical parkinsonism Parkinsonism Dyskinesia Rigidity Behavioral abnormalities Show more (+11) |
Bradykinesia
Behavioral abnormalities |
|
No
|
♀
|
C
|
NLD
|
18
|
n.a.
|
n.a.
|
Rigidity
Postural instability Behavioral abnormalities Parkinsonism Bradykinesia Tremor, action Gaze palsy Spasticity/pyramidal signs Tremor (any or unspecified) Dyskinesia Atypical parkinsonism Saccadic abnormalities Motor fluctuations Show more (+10) |
Behavioral abnormalities
Tremor (any or unspecified) |