Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
-Tremor (ictal)
Dysarthria (ictal) Ataxia, limb (ictal) Dysarthria Tremor (any or unspecified) Ataxia Ataxia (ictal) Ataxia, limb Dizziness Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
Dysarthria
-Gait ataxia (ictal) Ataxia Ataxia (ictal) Dizziness Dysarthria (ictal) Gait ataxia Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
Myokymia
Visual blurring Ataxia, limb (ictal) -Visual blurring (ictal) Ataxia, limb Ataxia Gait ataxia -Gait ataxia (ictal) Ataxia (ictal) Dysarthria Muscle weakness -Muscle weakness (ictal) Dysarthria (ictal) Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
Muscle weakness
Ataxia, limb Gait ataxia Vertigo -Tremor (ictal) Nausea Dysarthria (interictal) Visual blurring -Visual blurring (ictal) Headache Dysarthria -Gait ataxia (ictal) Tremor (any or unspecified) Nausea (ictal) Ataxia Ataxia (ictal) Myokymia Ataxia (interictal) Dysarthria (ictal) Vertigo (ictal) Ataxia, limb (ictal) -Muscle weakness (ictal) Headache (ictal) Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Ataxia
Ataxia, limb Visual blurring Muscle weakness -Visual blurring (ictal) Ataxia (ictal) -Muscle weakness (ictal) Ataxia, limb (ictal) Dysarthria (ictal) -Gait ataxia (ictal) Gait ataxia Dysarthria Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
-Gait ataxia (ictal)
Gait ataxia Dysarthria Ataxia (ictal) Dizziness Dysarthria (ictal) Ataxia Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
Nausea
Gait ataxia -Gait ataxia (ictal) Dysarthria Myokymia Ataxia Ataxia (ictal) Muscle weakness Nausea (ictal) -Muscle weakness (ictal) Ataxia, limb (ictal) Dysarthria (ictal) Ataxia, limb Dizziness Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
-Tremor (ictal)
Dysarthria (ictal) -Muscle weakness (ictal) Ataxia Vertigo (ictal) Dizziness Vertigo Tremor (any or unspecified) Ataxia (ictal) Dysarthria -Gait ataxia (ictal) Myokymia Gait ataxia Muscle weakness Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Gait ataxia
Dizziness Dysarthria (ictal) Dysarthria Vertigo (ictal) Nausea (ictal) Ataxia, limb Ataxia -Muscle weakness (ictal) Headache (ictal) Nausea Muscle weakness Vertigo Ataxia (ictal) Ataxia, limb (ictal) Myokymia -Gait ataxia (ictal) Headache Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
Muscle weakness
Nausea (ictal) -Gait ataxia (ictal) Ataxia, limb Dysarthria Ataxia Ataxia, limb (ictal) Ataxia (ictal) Gait ataxia Dysarthria (ictal) Dizziness Nausea -Muscle weakness (ictal) Myokymia Show more (+11) |
n.a.
|