Graves, 2010: Overview of all reported PxMD-KCNA1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
n.a.
|
16
|
39
|
Yes
|
Dysarthria
Dysarthria (ictal) Ataxia Tremor (any or unspecified) -Tremor (ictal) Ataxia, limb (ictal) Dizziness Ataxia (ictal) Ataxia, limb Show more (+6) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
42
|
Yes
|
Ataxia (ictal)
Ataxia Gait ataxia Dizziness -Gait ataxia (ictal) Dysarthria Dysarthria (ictal) Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
n.a.
|
6
|
23
|
Yes
|
Gait ataxia
Myokymia Dysarthria -Muscle weakness (ictal) Visual blurring Ataxia Ataxia (ictal) Ataxia, limb (ictal) Ataxia, limb Muscle weakness Dysarthria (ictal) -Gait ataxia (ictal) -Visual blurring (ictal) Show more (+10) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
5
|
50
|
Yes
|
Ataxia, limb (ictal)
Ataxia, limb Dysarthria (interictal) Muscle weakness Headache Nausea Dysarthria Nausea (ictal) Vertigo (ictal) Visual blurring -Muscle weakness (ictal) -Tremor (ictal) Myokymia Headache (ictal) Ataxia Tremor (any or unspecified) Gait ataxia Ataxia (interictal) -Visual blurring (ictal) Vertigo -Gait ataxia (ictal) Ataxia (ictal) Dysarthria (ictal) Show more (+20) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
8
|
21
|
Yes
|
Ataxia, limb
Gait ataxia Ataxia Muscle weakness -Visual blurring (ictal) Dysarthria Visual blurring Ataxia, limb (ictal) Dysarthria (ictal) -Gait ataxia (ictal) Ataxia (ictal) -Muscle weakness (ictal) Show more (+9) |
n.a.
|
|
No
|
♂
|
n.a.
|
n.a.
|
1
|
14
|
Yes
|
-Gait ataxia (ictal)
Dizziness Ataxia Dysarthria Dysarthria (ictal) Ataxia (ictal) Gait ataxia Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
14
|
n.a.
|
Yes
|
-Muscle weakness (ictal)
Ataxia (ictal) Gait ataxia -Gait ataxia (ictal) Dizziness Myokymia Nausea (ictal) Dysarthria (ictal) Ataxia, limb Muscle weakness Ataxia Dysarthria Nausea Ataxia, limb (ictal) Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
12
|
35
|
Yes
|
Gait ataxia
Ataxia Ataxia (ictal) Myokymia -Muscle weakness (ictal) Dizziness -Gait ataxia (ictal) Tremor (any or unspecified) Vertigo (ictal) -Tremor (ictal) Dysarthria (ictal) Muscle weakness Dysarthria Vertigo Show more (+11) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
15
|
36
|
Yes
|
Nausea (ictal)
Ataxia Ataxia, limb (ictal) -Muscle weakness (ictal) Nausea Ataxia (ictal) Dysarthria Dysarthria (ictal) Vertigo (ictal) Gait ataxia Headache -Gait ataxia (ictal) Ataxia, limb Muscle weakness Headache (ictal) Myokymia Vertigo Dizziness Show more (+15) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
n.a.
|
12
|
16
|
Yes
|
-Gait ataxia (ictal)
Dysarthria (ictal) Ataxia Dizziness Ataxia, limb (ictal) Nausea Ataxia, limb Nausea (ictal) Myokymia Gait ataxia -Muscle weakness (ictal) Muscle weakness Ataxia (ictal) Dysarthria Show more (+11) |
n.a.
|