Sauter, 2004: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
n.a.
|
3
|
5
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated Spastic gait |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
3
|
37
|
n.a.
|
Lower limb muscle weakness
Spasticity, lower limb Spastic gait Babinski sign -Pure or uncomplicated Show more (+2) |
n.a.
|
|
No
|
♀
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
Walking aids Hyperreflexia in upper limbs Lower limb muscle weakness Spastic gait -Pure or uncomplicated Cognitive impairment Show more (+4) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
n.a.
|
38
|
n.a.
|
Lower limb muscle weakness
Babinski sign Spasticity, lower limb Spastic gait -Pure or uncomplicated Show more (+2) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
1
|
8
|
No
|
Spasticity, lower limb
Babinski sign Lower limb muscle weakness -Pure or uncomplicated Show more (+1) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
55
|
n.a.
|
No
|
Spasticity, lower limb
Spastic gait Abnormality of the bladder -Pure or uncomplicated Lower limb muscle weakness Impaired vibratory sensation Babinski sign Show more (+4) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
3
|
53
|
No
|
Spasticity, lower limb
Abnormality of the bladder Walking aids Lower limb muscle weakness Wheelchair Babinski sign -Pure or uncomplicated Show more (+4) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Spastic gait
Spasticity, lower limb Lower limb muscle weakness -Pure or uncomplicated Babinski sign Show more (+2) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
3
|
n.a.
|
No
|
Babinski sign
Lower limb muscle weakness -Pure or uncomplicated Spasticity, lower limb Show more (+1) |
n.a.
|