Sauter, 2004: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
n.a.
|
3
|
5
|
n.a.
|
Spastic gait
-Pure or uncomplicated Spasticity, lower limb |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
3
|
37
|
n.a.
|
-Pure or uncomplicated
Babinski sign Lower limb muscle weakness Spasticity, lower limb Spastic gait Show more (+2) |
n.a.
|
|
No
|
♀
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Hyperreflexia in upper limbs
Spasticity, lower limb Cognitive impairment -Pure or uncomplicated Lower limb muscle weakness Spastic gait Walking aids Show more (+4) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
n.a.
|
38
|
n.a.
|
-Pure or uncomplicated
Babinski sign Lower limb muscle weakness Spasticity, lower limb Spastic gait Show more (+2) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
1
|
8
|
No
|
Lower limb muscle weakness
-Pure or uncomplicated Spasticity, lower limb Babinski sign Show more (+1) |
n.a.
|
|
Yes
|
♀
|
C
|
n.a.
|
55
|
n.a.
|
No
|
Abnormality of the bladder
Impaired vibratory sensation Spasticity, lower limb -Pure or uncomplicated Babinski sign Spastic gait Lower limb muscle weakness Show more (+4) |
n.a.
|
|
Yes
|
♂
|
C
|
n.a.
|
3
|
53
|
No
|
Walking aids
Lower limb muscle weakness Wheelchair Spasticity, lower limb Babinski sign -Pure or uncomplicated Abnormality of the bladder Show more (+4) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
Spastic gait -Pure or uncomplicated Lower limb muscle weakness Babinski sign Show more (+2) |
n.a.
|
|
No
|
♂
|
C
|
n.a.
|
3
|
n.a.
|
No
|
Spasticity, lower limb
-Pure or uncomplicated Lower limb muscle weakness Babinski sign Show more (+1) |
n.a.
|