Hedera, 2004: Overview of all reported HSP-ATL1 patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
D
USA
n.a.
n.a.
n.a.
Babinski sign
Pes cavus
Spastic gait
Lower limb muscle weakness
Tip-toe gait
-Pure or uncomplicated
Spasticity, lower limb
Show more (+4)
n.a.
No
D
USA
n.a.
n.a.
n.a.
Spastic gait
Babinski sign
-Pure or uncomplicated
Pes cavus
Spasticity, lower limb
Lower limb muscle weakness
Walking aids
Tip-toe gait
Show more (+5)
n.a.
No
D
USA
n.a.
n.a.
n.a.
Pes cavus
Babinski sign
Spastic gait
Spasticity, lower limb
Tip-toe gait
Lower limb muscle weakness
-Pure or uncomplicated
Show more (+4)
n.a.
No
D
USA
n.a.
n.a.
n.a.
Spastic gait
Tip-toe gait
Lower limb muscle weakness
-Pure or uncomplicated
Spasticity, lower limb
Babinski sign
Pes cavus
Show more (+4)
n.a.
Yes
D
USA
n.a.
5
n.a.
-Pure or uncomplicated
Spasticity, lower limb
Tip-toe gait
Pes cavus
Babinski sign
Spastic gait
Lower limb muscle weakness
Show more (+4)
n.a.
No
D
USA
n.a.
n.a.
n.a.
Spastic gait
Tip-toe gait
-Pure or uncomplicated
Lower limb muscle weakness
Spasticity, lower limb
Babinski sign
Pes cavus
Show more (+4)
n.a.