Ivanova, 2007: Overview of all reported HSP-ATL1 patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
n.a.
|
C
|
BEL
|
2
|
25
|
n.a.
|
Lower limb muscle weakness
-Pure or uncomplicated Babinski sign -Lower limb amyotrophy Spasticity, lower limb Spastic gait Show more (+3) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
1
|
12
|
n.a.
|
-Pure or uncomplicated
Walking aids Lower limb muscle weakness Spasticity, lower limb Babinski sign Show more (+2) |
n.a.
|
|
No
|
n.a.
|
C
|
BGR
|
5
|
39
|
n.a.
|
Spasticity, lower limb
Babinski sign Lower limb muscle weakness -Pure or uncomplicated Show more (+1) |
n.a.
|
|
Yes
|
n.a.
|
C
|
SWE
|
1
|
34
|
n.a.
|
Babinski sign
Walking aids Lower limb muscle weakness Spasticity, lower limb -Lower limb amyotrophy -Pure or uncomplicated Show more (+3) |
n.a.
|
|
No
|
n.a.
|
C
|
AUT
|
10
|
34
|
n.a.
|
Lower limb muscle weakness
-Lower limb amyotrophy Pes cavus Spastic gait Babinski sign Spasticity, lower limb Show more (+3) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
5
|
37
|
n.a.
|
Babinski sign
-Pure or uncomplicated Spasticity, lower limb Lower limb muscle weakness Show more (+1) |
n.a.
|
|
No
|
n.a.
|
C
|
AUT
|
10
|
20
|
n.a.
|
-Lower limb amyotrophy
Spastic gait -Pure or uncomplicated |
Spastic gait
|
|
Yes
|
♀
|
C
|
BEL
|
1
|
41
|
n.a.
|
Walking aids
Spasticity, lower limb -Lower limb amyotrophy -Pure or uncomplicated Babinski sign Hyperreflexia in upper limbs Lower limb muscle weakness Spastic gait Show more (+5) |
Spastic gait
|
|
No
|
n.a.
|
C
|
BGR
|
2
|
32
|
n.a.
|
Tip-toe gait
Babinski sign Walking aids -Pure or uncomplicated Spasticity, lower limb Lower limb muscle weakness Show more (+3) |
Tip-toe gait
|
|
No
|
n.a.
|
C
|
BEL
|
1
|
9
|
n.a.
|
Spastic gait
|