Tisher, 2016: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♀
|
n.a.
|
n.a.
|
7
|
39
|
n.a.
|
Spasticity, lower limb
Steppage gait Cognitive impairment Gait ataxia Mri brain other abnormalities Babinski sign Dysarthria Show more (+4) |
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
n.a.
|
5
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
No
|
♀
|
n.a.
|
n.a.
|
n.a.
|
8
|
n.a.
|
Spasticity, lower limb
|
n.a.
|