Falco, 2004: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
ITA
1
6
n.a.
Spasticity, lower limb
Spastic gait
Hyperreflexia in upper limbs
Babinski sign
-Pure or uncomplicated
-Lower limb amyotrophy
Show more (+3)
n.a.
Yes
n.a.
ITA
30
45
n.a.
-Pure or uncomplicated
Abnormality of the bladder
Babinski sign
Spastic gait
Spasticity, upper limb
Spasticity, lower limb
Hyperreflexia in upper limbs
Show more (+4)
n.a.
Yes
n.a.
ITA
25
32
n.a.
Hyperreflexia in upper limbs
-Pure or uncomplicated
Spastic gait
Spasticity, lower limb
Babinski sign
-Lower limb amyotrophy
Show more (+3)
n.a.