Lindsey, 2000: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
GBR
|
n.a.
|
11
|
n.a.
|
Impaired vibratory sensation
Hyperreflexia in upper limbs Impaired temperature sensation |
n.a.
|
|
Yes
|
♂
|
n.a.
|
GBR
|
60
|
75
|
n.a.
|
Spastic gait
Lower limb muscle weakness Abnormality of the bladder Spasticity, lower limb Impaired vibratory sensation Pes cavus Show more (+3) |
n.a.
|
|
Yes
|
n.a.
|
n.a.
|
GBR
|
40
|
70
|
No
|
Upper limb amyotrophy
-Lower limb amyotrophy Pes cavus |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
40
|
86
|
No
|
-Lower limb amyotrophy
Inability to walk Spastic gait Upper limb amyotrophy Cognitive impairment Pes cavus Wheelchair Show more (+4) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
GBR
|
n.a.
|
n.a.
|
n.a.
|
Impaired vibratory sensation
Cognitive impairment -Lower limb amyotrophy Spasticity, lower limb -Pure or uncomplicated Impaired pain sensation Show more (+3) |
n.a.
|