De, 2001: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
n.a.
USA
40
n.a.
n.a.
n.a.
n.a.
Yes
n.a.
USA
40
47
n.a.
-Pure or uncomplicated
Lower limb muscle weakness
Hyperreflexia in upper limbs
Abnormality of the bladder
Spasticity, lower limb
Babinski sign
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n.a.