Vandebona, 2012: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
n.a.
|
O
|
AUS
|
25
|
n.a.
|
n.a.
|
Spastic gait
Lower limb muscle weakness Impaired vibratory sensation Spasticity, lower limb -Pure or uncomplicated Abnormality of the bladder -Lower limb amyotrophy Walking aids Hyperreflexia in upper limbs Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
20
|
54
|
n.a.
|
Spasticity, lower limb
Babinski sign -Pure or uncomplicated Walking aids Abnormality of the bladder Spastic gait Show more (+3) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
4
|
73
|
n.a.
|
-Lower limb amyotrophy
Babinski sign Lower limb muscle weakness Impaired vibratory sensation Abnormality of the bladder Walking aids Hyperreflexia in upper limbs Spasticity, lower limb Spastic gait -Pure or uncomplicated Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
41
|
65
|
n.a.
|
Walking aids
Hyperreflexia in upper limbs Muscle weakness, upper limb Lower limb muscle weakness Spastic gait Babinski sign Spasticity, lower limb Wheelchair -Pure or uncomplicated Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
2
|
48
|
n.a.
|
Impaired vibratory sensation
Spastic gait Spasticity, lower limb Abnormality of the bladder Muscle weakness, upper limb Wheelchair Hyperreflexia in upper limbs Lower limb muscle weakness Babinski sign Walking aids Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
2
|
60
|
n.a.
|
Impaired vibratory sensation
Babinski sign Walking aids Hyperreflexia in upper limbs Spasticity, lower limb Lower limb muscle weakness -Pure or uncomplicated Spastic gait Abnormality of the bladder Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
n.a.
|
55
|
n.a.
|
Lower limb muscle weakness
Walking aids Spasticity, lower limb Impaired vibratory sensation Spastic gait Babinski sign Hyperreflexia in upper limbs Abnormality of the bladder -Pure or uncomplicated Show more (+6) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
32
|
38
|
n.a.
|
Hyperreflexia in upper limbs
Spastic gait Spasticity, lower limb -Pure or uncomplicated Show more (+1) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
10
|
48
|
n.a.
|
Walking aids
Abnormality of the bladder Hyperreflexia in upper limbs Spasticity, upper limb Lower limb muscle weakness Spastic gait Impaired vibratory sensation Babinski sign Ataxia, limb Spasticity, lower limb Show more (+7) |
n.a.
|
|
Yes
|
n.a.
|
O
|
AUS
|
n.a.
|
n.a.
|
n.a.
|
-Lower limb amyotrophy
Spastic gait Babinski sign Hyperreflexia in upper limbs Lower limb muscle weakness Spasticity, lower limb -Pure or uncomplicated Walking aids Show more (+5) |
n.a.
|