Nanetti, 2012: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
ITA
|
38
|
51
|
n.a.
|
Spasticity, lower limb
Abnormality of the bladder |
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
57
|
65
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
Yes
|
♀
|
C
|
ITA
|
10
|
17
|
n.a.
|
n.a.
|
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
14
|
24
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
No
|
♀
|
C
|
ITA
|
40
|
49
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
Yes
|
♀
|
C
|
ITA
|
40
|
69
|
n.a.
|
Lower limb muscle weakness
Impaired vibratory sensation Abnormality of the bladder Spasticity, lower limb Show more (+1) |
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
5
|
16
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
20
|
39
|
n.a.
|
Spasticity, lower limb
|
n.a.
|
|
Yes
|
♀
|
C
|
ITA
|
50
|
58
|
n.a.
|
Spasticity, lower limb
-Lower limb amyotrophy Impaired vibratory sensation Abnormality of the bladder Lower limb muscle weakness Show more (+2) |
n.a.
|
|
Yes
|
♀
|
C
|
ITA
|
50
|
55
|
n.a.
|
Abnormality of the bladder
Spasticity, lower limb |
n.a.
|