Reddy, 2007: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
n.a.
|
USA
|
25
|
51
|
n.a.
|
Spasticity, lower limb
Hyperreflexia in upper limbs Walking aids Spastic gait Lower limb muscle weakness -Pure or uncomplicated Babinski sign Show more (+4) |
n.a.
|
|
Yes
|
♀
|
n.a.
|
USA
|
24
|
48
|
n.a.
|
Spastic gait
-Pure or uncomplicated Babinski sign Spasticity, lower limb Lower limb muscle weakness Hyperreflexia in upper limbs Show more (+3) |
n.a.
|
|
No
|
♂
|
n.a.
|
USA
|
3
|
23
|
n.a.
|
Lower limb muscle weakness
Babinski sign Hyperreflexia in upper limbs -Pure or uncomplicated Spastic gait Spasticity, lower limb Show more (+3) |
n.a.
|