Ribaï, 2008: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
C
FRA
4
22
n.a.
Babinski sign
Hyperreflexia in upper limbs
Spastic gait
n.a.
No
C
FRA
1
27
n.a.
Abnormality of the bladder
Spastic gait
Babinski sign
Impaired vibratory sensation
Show more (+1)
n.a.
No
C
FRA
n.a.
63
n.a.
Hyperreflexia in upper limbs
Babinski sign
Spastic gait
Abnormality of the bladder
Wheelchair
Impaired vibratory sensation
Inability to walk
Global developmental delay
Show more (+5)
n.a.
No
C
FRA
0
43
n.a.
Inability to walk
Impaired vibratory sensation
Global developmental delay
Spastic gait
Cerebellar atrophy
Mri brain other abnormalities
Wheelchair
Mri spine abnormalities
Babinski sign
Abnormality of the bladder
Show more (+7)
n.a.
No
C
FRA
4
47
n.a.
Cognitive impairment
Mri brain other abnormalities
Spastic gait
Global developmental delay
Impaired vibratory sensation
Babinski sign
Mri spine abnormalities
Abnormality of the bladder
Inability to walk
Wheelchair
Hyperreflexia in upper limbs
Show more (+8)
n.a.
No
C
FRA
n.a.
24
n.a.
Babinski sign
Spastic gait
n.a.
No
C
FRA
5
45
n.a.
Abnormality of the bladder
Spastic gait
Hyperreflexia in upper limbs
Impaired vibratory sensation
Walking aids
Babinski sign
Global developmental delay
Show more (+4)
n.a.
No
C
FRA
n.a.
39
n.a.
Hyperreflexia in upper limbs
Babinski sign
Inability to walk
Tip-toe gait
Spastic gait
Wheelchair
Impaired vibratory sensation
Global developmental delay
Show more (+5)
n.a.
No
C
FRA
n.a.
49
n.a.
Hyperreflexia in upper limbs
Impaired vibratory sensation
n.a.
Yes
C
FRA
n.a.
53
n.a.
Babinski sign
Abnormality of the bladder
Impaired vibratory sensation
Hyperreflexia in upper limbs
Global developmental delay
Abnormality of the cerebral white matter
Spastic gait
Mri spine abnormalities
Walking aids
Cerebellar atrophy
Mri brain other abnormalities
Show more (+8)
n.a.