Mead, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
GBR
|
35
|
38
|
n.a.
|
Abnormality of the bladder
|
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
35
|
40
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
35
|
57
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
60
|
82
|
n.a.
|
Impaired vibratory sensation
Abnormality of the bladder Walking aids |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
45
|
71
|
n.a.
|
Impaired vibratory sensation
Inability to walk Walking aids Abnormality of the bladder Wheelchair Show more (+2) |
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
27
|
29
|
n.a.
|
n.a.
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
24
|
32
|
n.a.
|
Impaired vibratory sensation
Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
25
|
50
|
n.a.
|
Impaired proprioception
Lower limb muscle weakness Impaired pain sensation Abnormality of the cerebral white matter Hyperreflexia in upper limbs Walking aids Spasticity, lower limb Impaired temperature sensation Mri brain other abnormalities Impaired vibratory sensation Abnormality of the bladder Show more (+8) |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
34
|
64
|
n.a.
|
Seizures
Impaired vibratory sensation Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
0
|
30
|
n.a.
|
Ataxia, limb
|
n.a.
|