Mead, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
GBR
|
35
|
38
|
n.a.
|
Abnormality of the bladder
|
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
35
|
40
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
35
|
57
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
60
|
82
|
n.a.
|
Abnormality of the bladder
Walking aids Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
45
|
71
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation Walking aids Inability to walk Wheelchair Show more (+2) |
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
27
|
29
|
n.a.
|
n.a.
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
24
|
32
|
n.a.
|
Abnormality of the bladder
Impaired vibratory sensation |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
25
|
50
|
n.a.
|
Mri brain other abnormalities
Impaired temperature sensation Hyperreflexia in upper limbs Impaired pain sensation Impaired proprioception Walking aids Abnormality of the bladder Lower limb muscle weakness Spasticity, lower limb Impaired vibratory sensation Abnormality of the cerebral white matter Show more (+8) |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
34
|
64
|
n.a.
|
Seizures
Impaired vibratory sensation Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
0
|
30
|
n.a.
|
Ataxia, limb
|
n.a.
|