Mead, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
GBR
|
35
|
38
|
n.a.
|
Abnormality of the bladder
|
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
35
|
40
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
35
|
57
|
n.a.
|
Impaired vibratory sensation
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
60
|
82
|
n.a.
|
Impaired vibratory sensation
Walking aids Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
45
|
71
|
n.a.
|
Walking aids
Wheelchair Inability to walk Impaired vibratory sensation Abnormality of the bladder Show more (+2) |
n.a.
|
|
No
|
♂
|
n.a.
|
GBR
|
27
|
29
|
n.a.
|
n.a.
|
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
24
|
32
|
n.a.
|
Impaired vibratory sensation
Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
25
|
50
|
n.a.
|
Walking aids
Spasticity, lower limb Mri brain other abnormalities Impaired vibratory sensation Abnormality of the cerebral white matter Hyperreflexia in upper limbs Impaired pain sensation Lower limb muscle weakness Impaired proprioception Impaired temperature sensation Abnormality of the bladder Show more (+8) |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
34
|
64
|
n.a.
|
Impaired vibratory sensation
Seizures Abnormality of the bladder |
n.a.
|
|
No
|
♀
|
n.a.
|
GBR
|
0
|
30
|
n.a.
|
Ataxia, limb
|
n.a.
|