Mead, 2001: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
No
n.a.
GBR
35
38
n.a.
Abnormality of the bladder
n.a.
No
n.a.
GBR
35
40
n.a.
Impaired vibratory sensation
n.a.
No
n.a.
GBR
35
57
n.a.
Impaired vibratory sensation
n.a.
No
n.a.
GBR
60
82
n.a.
Impaired vibratory sensation
Walking aids
Abnormality of the bladder
n.a.
No
n.a.
GBR
45
71
n.a.
Walking aids
Wheelchair
Inability to walk
Impaired vibratory sensation
Abnormality of the bladder
Show more (+2)
n.a.
No
n.a.
GBR
27
29
n.a.
n.a.
n.a.
No
n.a.
GBR
24
32
n.a.
Impaired vibratory sensation
Abnormality of the bladder
n.a.
No
n.a.
GBR
25
50
n.a.
Walking aids
Spasticity, lower limb
Mri brain other abnormalities
Impaired vibratory sensation
Abnormality of the cerebral white matter
Hyperreflexia in upper limbs
Impaired pain sensation
Lower limb muscle weakness
Impaired proprioception
Impaired temperature sensation
Abnormality of the bladder
Show more (+8)
n.a.
No
n.a.
GBR
34
64
n.a.
Impaired vibratory sensation
Seizures
Abnormality of the bladder
n.a.
No
n.a.
GBR
0
30
n.a.
Ataxia, limb
n.a.