Higgins, 2001: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Lower limb muscle weakness
-Pure or uncomplicated |
n.a.
|
|
No
|
♀
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated |
n.a.
|
|
No
|
♀
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness |
n.a.
|
|
No
|
♀
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated |
n.a.
|
|
No
|
♂
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated |
n.a.
|
|
Yes
|
♀
|
C
|
USA
|
n.a.
|
n.a.
|
n.a.
|
-Pure or uncomplicated
Lower limb muscle weakness |
n.a.
|