Santorelli, 2000: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
n.a.
|
C
|
ITA
|
n.a.
|
23
|
n.a.
|
-Pure or uncomplicated
Hyperreflexia in upper limbs |
n.a.
|
|
No
|
♂
|
C
|
ITA
|
40
|
58
|
n.a.
|
Spasticity, lower limb
-Pure or uncomplicated Babinski sign Spastic gait Hyperreflexia in upper limbs Show more (+2) |
n.a.
|
|
No
|
♀
|
C
|
ITA
|
40
|
70
|
n.a.
|
n.a.
|
||
No
|
♀
|
C
|
ITA
|
55
|
63
|
n.a.
|
Abnormality of the bladder
Spastic gait Babinski sign -Pure or uncomplicated Spasticity, lower limb Show more (+2) |
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
n.a.
|
30
|
n.a.
|
Wheelchair
Inability to walk Babinski sign -Pure or uncomplicated Spasticity, lower limb Show more (+2) |
n.a.
|
|
No
|
n.a.
|
C
|
ITA
|
n.a.
|
32
|
n.a.
|
n.a.
|