Santorelli, 2000: Overview of all reported HSP-SPAST patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
n.a.
|
C
|
ITA
|
n.a.
|
23
|
n.a.
|
Hyperreflexia in upper limbs
-Pure or uncomplicated |
n.a.
|
|
No
|
♂
|
C
|
ITA
|
40
|
58
|
n.a.
|
Spasticity, lower limb
Spastic gait Hyperreflexia in upper limbs Babinski sign -Pure or uncomplicated Show more (+2) |
n.a.
|
|
No
|
♀
|
C
|
ITA
|
40
|
70
|
n.a.
|
n.a.
|
||
No
|
♀
|
C
|
ITA
|
55
|
63
|
n.a.
|
-Pure or uncomplicated
Abnormality of the bladder Babinski sign Spastic gait Spasticity, lower limb Show more (+2) |
n.a.
|
|
Yes
|
♂
|
C
|
ITA
|
n.a.
|
30
|
n.a.
|
Spasticity, lower limb
Babinski sign Wheelchair Inability to walk -Pure or uncomplicated Show more (+2) |
n.a.
|
|
No
|
n.a.
|
C
|
ITA
|
n.a.
|
32
|
n.a.
|
n.a.
|