Ivanova, 2006: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
BGR
40
50
n.a.
Spasticity, lower limb
Pes cavus
-Pure or uncomplicated
Spastic gait
Show more (+1)
n.a.
p.Cys171*: het
No
n.a.
BGR
6
13
n.a.
Abnormality of the skeletal system
Lower limb muscle weakness
Hyperreflexia in upper limbs
Spasticity, lower limb
Spastic gait
Pes cavus
Show more (+3)
n.a.
No
n.a.
BGR
2
10
n.a.
Spastic gait
Abnormality of the bladder
Spasticity, lower limb
-Pure or uncomplicated
Show more (+1)
n.a.
No
n.a.
BGR
24
57
n.a.
Spasticity, lower limb
Spastic gait
-Pure or uncomplicated
n.a.
p.Cys171*: het
Yes
n.a.
BGR
17
18
n.a.
-Pure or uncomplicated
Spastic gait
Spasticity, lower limb
n.a.
No
n.a.
BGR
14
31
n.a.
Hyperreflexia in upper limbs
Spastic gait
Abnormality of the skeletal system
Lower limb muscle weakness
Spasticity, lower limb
Cognitive impairment
Pes cavus
Show more (+4)
n.a.
Yes
n.a.
BGR
35
40
n.a.
Hyperreflexia in upper limbs
Abnormality of the bladder
Spastic gait
Pes cavus
-Pure or uncomplicated
Spasticity, lower limb
Show more (+3)
n.a.
c.683-1G>A: het
No
n.a.
BGR
2
12
n.a.
Pes cavus
Lower limb muscle weakness
-Pure or uncomplicated
Spasticity, lower limb
Spastic gait
Show more (+2)
n.a.
No
n.a.
BGR
55
57
n.a.
-Pure or uncomplicated
Spastic gait
Spasticity, lower limb
n.a.
c.683-1G>A: het
Yes
n.a.
BGR
7
42
n.a.
-Pure or uncomplicated
Spasticity, lower limb
Hyperreflexia in upper limbs
Lower limb muscle weakness
Spastic gait
Abnormality of the bladder
Show more (+3)
n.a.