Ivanova, 2006: Overview of all reported HSP-SPAST patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
BGR
40
50
n.a.
Spastic gait
Spasticity, lower limb
Pes cavus
-Pure or uncomplicated
Show more (+1)
n.a.
p.Cys171*: het
No
n.a.
BGR
6
13
n.a.
Hyperreflexia in upper limbs
Spasticity, lower limb
Spastic gait
Pes cavus
Abnormality of the skeletal system
Lower limb muscle weakness
Show more (+3)
n.a.
No
n.a.
BGR
2
10
n.a.
-Pure or uncomplicated
Abnormality of the bladder
Spasticity, lower limb
Spastic gait
Show more (+1)
n.a.
No
n.a.
BGR
24
57
n.a.
Spasticity, lower limb
-Pure or uncomplicated
Spastic gait
n.a.
p.Cys171*: het
Yes
n.a.
BGR
17
18
n.a.
Spastic gait
-Pure or uncomplicated
Spasticity, lower limb
n.a.
No
n.a.
BGR
14
31
n.a.
Cognitive impairment
Hyperreflexia in upper limbs
Spasticity, lower limb
Lower limb muscle weakness
Pes cavus
Spastic gait
Abnormality of the skeletal system
Show more (+4)
n.a.
Yes
n.a.
BGR
35
40
n.a.
Pes cavus
Spasticity, lower limb
-Pure or uncomplicated
Abnormality of the bladder
Hyperreflexia in upper limbs
Spastic gait
Show more (+3)
n.a.
c.683-1G>A: het
No
n.a.
BGR
2
12
n.a.
Pes cavus
Lower limb muscle weakness
-Pure or uncomplicated
Spastic gait
Spasticity, lower limb
Show more (+2)
n.a.
No
n.a.
BGR
55
57
n.a.
Spasticity, lower limb
-Pure or uncomplicated
Spastic gait
n.a.
c.683-1G>A: het
Yes
n.a.
BGR
7
42
n.a.
Hyperreflexia in upper limbs
Spastic gait
Lower limb muscle weakness
-Pure or uncomplicated
Abnormality of the bladder
Spasticity, lower limb
Show more (+3)
n.a.