Unknown, 2011: Overview of all reported DYT/PARK-PTS patients

Index patient Sex Ethnicity Country of origin AAO AAE Family history Symptoms Initial symptoms Reported mutations
Yes
n.a.
n.a.
n.a.
n.a.
20
No
Hyperreflexia
Spasticity
Muscular hypotonia
Abnormal central motor function
Seizures
Autonomic sign/sympt.
Cognitive impairment
Intellectual developmental disorder
Abnormality of the sense of smell
Microcephaly
Global developmental delay
Show more (+8)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
15
No
Autonomic sign/sympt.
Muscular hypotonia
Hyperreflexia
Microcephaly
Seizures
Intellectual developmental disorder
Spasticity
Abnormality of the sense of smell
Cognitive impairment
Global developmental delay
Abnormal central motor function
Show more (+8)
n.a.
p.Asn52Ser: hom
Yes
n.a.
n.a.
n.a.
n.a.
28
No
Cognitive impairment
Intellectual developmental disorder
Muscular hypotonia
Global developmental delay
Hyperreflexia
Seizures
Abnormal central motor function
Spasticity
Show more (+5)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
18
No
Spasticity
Abnormal central motor function
Intellectual developmental disorder
Global developmental delay
Cognitive impairment
Hyperreflexia
Muscular hypotonia
Show more (+4)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
33
No
Muscular hypotonia
Cognitive impairment
Abnormal central motor function
Hyperreflexia
Intellectual developmental disorder
Global developmental delay
Spasticity
Show more (+4)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
2
No
Hyperreflexia
Intellectual developmental disorder
Muscular hypotonia
Cognitive impairment
Global developmental delay
Autonomic sign/sympt.
Spasticity
Abnormal central motor function
Microcephaly
Seizures
Show more (+7)
n.a.
p.Asn52Ser: hom
Yes
n.a.
n.a.
n.a.
n.a.
17
No
Hyperreflexia
Spasticity
Abnormality of the sense of smell
Cognitive impairment
Seizures
Muscular hypotonia
Intellectual developmental disorder
Abnormal central motor function
Global developmental delay
Show more (+6)
n.a.
p.Asn52Ser: hom
Yes
n.a.
n.a.
n.a.
n.a.
13
No
Autonomic sign/sympt.
Microcephaly
Seizures
Abnormal central motor function
Muscular hypotonia
Intellectual developmental disorder
Hyperreflexia
Cognitive impairment
Abnormality of the sense of smell
Spasticity
Global developmental delay
Show more (+8)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
24
No
Hyperreflexia
Global developmental delay
Spasticity
Autonomic sign/sympt.
Seizures
Abnormal central motor function
Intellectual developmental disorder
Muscular hypotonia
Cognitive impairment
Show more (+6)
n.a.
Yes
n.a.
n.a.
n.a.
n.a.
25
No
Abnormal central motor function
Seizures
Cognitive impairment
Hyperreflexia
Muscular hypotonia
Intellectual developmental disorder
Global developmental delay
Spasticity
Show more (+5)
n.a.