Wirth, 2017: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
FRA
|
27
|
n.a.
|
n.a.
|
Cognitive impairment
Bradykinesia Datscan/trodat with evidence of dopaminergic deficit Rigidity Anxiety Dyskinesia Tremor (any or unspecified) Abnormal central motor function NMS parkinsonism Normal brain mri Resting tremor Psychosis Psychiatric disorders Tremor, limb Motor fluctuations Parkinsonism Show more (+13) |
Anxiety
Resting tremor |
|
Yes
|
♂
|
C
|
FRA
|
23
|
n.a.
|
n.a.
|
Psychiatric disorders
Dystonia, leg NMS parkinsonism Normal brain mri Psychosis Rigidity Parkinsonism Bradykinesia Dystonia (any or unspecified) Muscular hypotonia Motor fluctuations Datscan/trodat with evidence of dopaminergic deficit Dyskinesia Dystonia, limb Abnormal central motor function Dystonia, focal Anxiety Depression Show more (+15) |
Anxiety
Depression |