Wirth, 2017: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
FRA
|
27
|
n.a.
|
n.a.
|
Bradykinesia
Resting tremor Normal brain mri Datscan/trodat with evidence of dopaminergic deficit Motor fluctuations Dyskinesia Tremor (any or unspecified) Parkinsonism NMS parkinsonism Rigidity Psychosis Tremor, limb Abnormal central motor function Cognitive impairment Anxiety Psychiatric disorders Show more (+13) |
Resting tremor
Anxiety |
|
Yes
|
♂
|
C
|
FRA
|
23
|
n.a.
|
n.a.
|
Parkinsonism
Dystonia, limb Normal brain mri Dystonia, leg Dystonia, focal Psychiatric disorders Abnormal central motor function Datscan/trodat with evidence of dopaminergic deficit Dystonia (any or unspecified) Bradykinesia Anxiety Muscular hypotonia Psychosis Motor fluctuations Dyskinesia Rigidity Depression NMS parkinsonism Show more (+15) |
Anxiety
Depression |