Wirth, 2017: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
C
|
FRA
|
27
|
n.a.
|
n.a.
|
Dyskinesia
Psychiatric disorders NMS parkinsonism Cognitive impairment Tremor (any or unspecified) Bradykinesia Motor fluctuations Psychosis Anxiety Resting tremor Parkinsonism Rigidity Datscan/trodat with evidence of dopaminergic deficit Abnormal central motor function Normal brain mri Tremor, limb Show more (+13) |
Anxiety
Resting tremor |
|
Yes
|
♂
|
C
|
FRA
|
23
|
n.a.
|
n.a.
|
Dystonia (any or unspecified)
NMS parkinsonism Dystonia, limb Dystonia, leg Muscular hypotonia Motor fluctuations Depression Abnormal central motor function Datscan/trodat with evidence of dopaminergic deficit Normal brain mri Rigidity Psychiatric disorders Anxiety Parkinsonism Psychosis Bradykinesia Dyskinesia Dystonia, focal Show more (+15) |
Depression
Anxiety |