Yoshino, 2010: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
JPN
|
25
|
34
|
n.a.
|
NMS parkinsonism
Parkinsonism Bradykinesia Rigidity Mri brain other abnormalities Cognitive impairment Abnormal central motor function Motor fluctuations Gait disturbance Dyskinesia Postural instability Autonomic sign/sympt. Show more (+9) |
Gait disturbance
|
|
Yes
|
♀
|
n.a.
|
JPN
|
20
|
35
|
n.a.
|
Cognitive impairment
Tremor (any or unspecified) NMS parkinsonism Bradykinesia Sleep benefit Mri brain other abnormalities Parkinsonism Postural instability Psychosis Depression Dyskinesia Psychiatric disorders Hypointensity on basal ganglia and or nigra Resting tremor Gait disturbance Abnormal central motor function Motor fluctuations Rigidity Autonomic sign/sympt. Show more (+16) |
n.a.
|
|
No
|
♂
|
n.a.
|
JPN
|
30
|
38
|
n.a.
|
Postural instability
Parkinsonism Motor fluctuations Dyskinesia Psychiatric disorders Autonomic sign/sympt. NMS parkinsonism Gait disturbance Cognitive impairment Abnormal central motor function Rigidity Bradykinesia Mri brain other abnormalities Show more (+10) |
Gait disturbance
|