Yoshino, 2010: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
JPN
|
25
|
34
|
n.a.
|
Bradykinesia
Parkinsonism Mri brain other abnormalities Motor fluctuations Cognitive impairment Postural instability Gait disturbance Abnormal central motor function Rigidity Dyskinesia NMS parkinsonism Autonomic sign/sympt. Show more (+9) |
Gait disturbance
|
|
Yes
|
♀
|
n.a.
|
JPN
|
20
|
35
|
n.a.
|
Depression
Tremor (any or unspecified) Dyskinesia Abnormal central motor function Rigidity Bradykinesia Cognitive impairment Sleep benefit Parkinsonism Hypointensity on basal ganglia and or nigra Psychiatric disorders Psychosis Resting tremor NMS parkinsonism Motor fluctuations Postural instability Mri brain other abnormalities Autonomic sign/sympt. Gait disturbance Show more (+16) |
n.a.
|
|
No
|
♂
|
n.a.
|
JPN
|
30
|
38
|
n.a.
|
Autonomic sign/sympt.
Cognitive impairment Rigidity Gait disturbance Abnormal central motor function Postural instability Psychiatric disorders Dyskinesia Bradykinesia NMS parkinsonism Mri brain other abnormalities Motor fluctuations Parkinsonism Show more (+10) |
Gait disturbance
|