Yoshino, 2010: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
Yes
|
♂
|
n.a.
|
JPN
|
25
|
34
|
n.a.
|
Postural instability
Dyskinesia Abnormal central motor function Cognitive impairment Parkinsonism Mri brain other abnormalities Bradykinesia Motor fluctuations Autonomic sign/sympt. Rigidity NMS parkinsonism Gait disturbance Show more (+9) |
Gait disturbance
|
|
Yes
|
♀
|
n.a.
|
JPN
|
20
|
35
|
n.a.
|
Depression
Sleep benefit Dyskinesia Tremor (any or unspecified) Psychosis Postural instability Rigidity NMS parkinsonism Bradykinesia Hypointensity on basal ganglia and or nigra Gait disturbance Autonomic sign/sympt. Psychiatric disorders Mri brain other abnormalities Resting tremor Cognitive impairment Parkinsonism Abnormal central motor function Motor fluctuations Show more (+16) |
n.a.
|
|
No
|
♂
|
n.a.
|
JPN
|
30
|
38
|
n.a.
|
Motor fluctuations
Parkinsonism Cognitive impairment Dyskinesia Psychiatric disorders Rigidity Postural instability Gait disturbance NMS parkinsonism Abnormal central motor function Autonomic sign/sympt. Bradykinesia Mri brain other abnormalities Show more (+10) |
Gait disturbance
|