Sina, 2009: Overview of all reported DYT/PARK-PLA2G6-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♀
|
n.a.
|
IRN
|
21
|
23
|
n.a.
|
Hand tremor
Abnormal eye movement Dystonia (any or unspecified) Dystonia, arm Dysarthria Cognitive impairment NMS parkinsonism Gait disturbance Abnormal central motor function Mri brain other abnormalities Postural instability Rigidity Depression Dystonia, leg Bradykinesia Parkinsonism Tremor (any or unspecified) Dyskinesia Dystonia, limb Pyramidal sign Show more (+17) |
n.a.
|
|
Yes
|
♂
|
n.a.
|
IRN
|
25
|
31
|
n.a.
|
Parkinsonism
Dystonia, limb Tremor (any or unspecified) Dystonia (any or unspecified) Pyramidal sign Depression Gait disturbance Abnormal eye movement Cognitive impairment Rigidity Dyskinesia Mri brain other abnormalities NMS parkinsonism Dystonia, leg Postural instability Abnormal central motor function Bradykinesia Hand tremor Dysarthria Dystonia, arm Show more (+17) |
n.a.
|
|
No
|
♂
|
n.a.
|
IRN
|
22
|
25
|
n.a.
|
Abnormal central motor function
Dystonia (any or unspecified) Parkinsonism Dystonia, limb Dyskinesia Dysarthria Mri brain other abnormalities Pyramidal sign Hand tremor Dystonia, leg Abnormal eye movement Tremor (any or unspecified) Postural instability Cognitive impairment Gait disturbance Rigidity Dystonia, arm Bradykinesia Show more (+15) |
n.a.
|