Vroegindeweij, 2017: Overview of all reported DYT/PARK-CP-(NBIA) patients
| Index patient | Sex | Ethnicity | Country of origin | AAO | AAE | Family history | Symptoms | Initial symptoms | Reported mutations |
|---|---|---|---|---|---|---|---|---|---|
No
|
♂
|
C
|
NLD
|
48
|
50
|
n.a.
|
Other mri abnormality
Dysarthria Dystonia, generalized Bradykinesia Parkinsonism Gait impairment Dystonia (any or unspecified) Orofacial dyskinesia Abnormal central motor function Chorea Dyskinesia Postural instability Hypointensity on basal ganglia and or nigra Ataxia Show more (+11) |
Gait impairment
Orofacial dyskinesia Chorea |
|
No
|
♂
|
C
|
NLD
|
54
|
56
|
n.a.
|
Dysarthria
Gait impairment Depression Abnormal central motor function Other mri abnormality Hypointensity on basal ganglia and or nigra Postural instability Diabetes mellitus Ataxia Cognitive impairment Bradykinesia Behavioral abnormality Show more (+9) |
Dysarthria
Gait impairment Behavioral abnormality |
|
Yes
|
♀
|
C
|
NLD
|
51
|
59
|
No
|
Anxiety
Behavioral abnormality Dysarthria Diabetes mellitus Anemia NMS parkinsonism Gait impairment Other mri abnormality Depression Abnormal central motor function Postural instability Parkinsonism Dyskinesia Orofacial dyskinesia Hypointensity on basal ganglia and or nigra Ataxia Bradykinesia Cognitive impairment Chorea Show more (+16) |
Orofacial dyskinesia
|
|
Yes
|
♂
|
C
|
NLD
|
n.a.
|
56
|
n.a.
|
Dysarthria
Anemia Postural instability Behavioral abnormality Parkinsonism Diabetes mellitus Gait impairment NMS parkinsonism Depression Cognitive impairment Bradykinesia Ataxia Abnormal central motor function Show more (+10) |
Behavioral abnormality
|
|
Yes
|
♂
|
C
|
ITA
|
40
|
56
|
No
|
Bradykinesia
Postural instability Cognitive impairment Ataxia Diabetes mellitus Dysarthria Other mri abnormality Hypointensity on basal ganglia and or nigra Parkinsonism Anemia Abnormal central motor function NMS parkinsonism Gait impairment Show more (+10) |
Dysarthria
|